Key Documents
Jonathan M. Irish, Ph.D.
Academic Appointments
- Instructor, Medicine - Oncology
Professional Snapshot
Honors and Awards
- Fellow of the Leukemia and Lymphoma Society, Leukemia and Lymphoma Society (2005-2008)
- Postdoctoral Fellowship in Immunology, Stanford University (2004-2005)
- G.J. Lieberman Graduate Fellow, Stanford University (2003-2004)
- James H. Clark Graduate Fellow, Stanford University (2000-2003)
Professional Education
| Bachelor of Science, Chemistry: | University of Michigan, Chemistry (1998) |
| Bachelor of Science: | University of Michigan, Biochemistry (1998) |
| Bachelor of Science: | University of Michigan, Biology (1998) |
Web Site Links
Scientific Focus
Research Interests
I am a PhD research scientist who is passionate about clinical cancer research and the use of advanced technology to improve cancer therapy. My current goal is to combine bioinformatics techniques and immunology research in order to understand why cancer patients' cells resist existing therapies. I am especially interested in the critical choice of the first therapy for the patient. We are currently applying this approach to study signaling in leukemia and lymphoma.
Publications
- Single-cell profiling identifies aberrant STAT5 activation in myeloid malignancies with specific clinical and biologic correlates. Cancer Cell. 2008; (4): 335-43
- Kinetics of B cell receptor signaling in human B cell subsets mapped by phosphospecific flow cytometry. J Immunol. 2006; (3): 1581-9
- Altered B-cell receptor signaling kinetics distinguish human follicular lymphoma B cells from tumor-infiltrating nonmalignant B cells. Blood. 2006; (9): 3135-42
- Mapping normal and cancer cell signalling networks: towards single-cell proteomics. Nat Rev Cancer. 2006; (2): 146-55
- Single cell profiling of potentiated phospho-protein networks in cancer cells. Cell. 2004; (2): 217-28
AIDS impact on Africa’s children 
